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Plasmaféresis indicada por enfermedad neurológica: experiencia de 140 procedimientos en 47 pacientes / Plasmapheresis in neurological diseases: experience in 140 procedures in 47 patients
Nogales-Gaete, Jorge; Valenzuela T., Daniel; Liendo P., Federico; Vidal A., Pamela; Gil F., Gloria; Sßez M., David.
  • Nogales-Gaete, Jorge; Universidad de Chile. Campus Sur. Facultad de Medicina. Departamento de Neurología. CL
  • Valenzuela T., Daniel; Universidad de Chile. Campus Sur. Facultad de Medicina. Departamento de Neurología. CL
  • Liendo P., Federico; Hospital Barros Luco-Trudeau. Servicio de Banco de Sangre. CL
  • Vidal A., Pamela; Hospital Barros Luco-Trudeau. Servicio de Banco de Sangre. CL
  • Gil F., Gloria; Hospital Barros Luco-Trudeau. Servicio de Banco de Sangre. CL
  • Sßez M., David; Universidad de Chile. Campus Sur. Facultad de Medicina. Departamento de Neurología. CL
Rev. méd. Chile ; 132(3): 295-298, mar. 2004. tab
Article Dans Espagnol | LILACS | ID: lil-384170
ABSTRACT

Background:

Plasmapheresis can be useful in myasthenia gravis, Guillain BarrÚ syndrome and chronic demyelinating inflamatory polyradiculoneuritis.

Aim:

To report our experience with plasmapheresis in patients with neurological diseases. Material and

methods:

Retrospective review of plasmapheresis procedures done between 1995 and 2001, in a public hospital. Indications criteria, clinical results and technical yield were analyzed.

Results:

One hundred fifty nine procedures were reviewed. One hundred forty (88 percent) were indicated for neurological diseases (44 percent for Guillain BarrÚ syndrome and 29 percent for myasthenia gravis). Clinical improvement or eventual complications were avoided in 70 percent of patients with Guillain BarrÚ syndrome and 100 percent of patients with myasthenia gravis. Hypotension in 10 percent and paresthesias in 7 percent were observed. All complications were successfully controlled with crystalloid or fresh plasma infusions or citrate management. In 11 cases, the procedure was interrupted due to obstruction of the venous access, that was peripheral in eight of these. The most common difficulties of the procedure were delay in performing it in 50 percent of patients and insufficient exchange volumes in 30 percent.

Conclusions:

Plasmapheresis was safe and useful in patients with myasthenia gravis and Guillain BarrÚ syndrome. The drawbacks of the procedure are its costs and requirement of special equipment (Rev MÚd Chile 2004; 132 295-8).
Sujets)
Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Plasmaphérèse / Maladies du système nerveux Limites du sujet: Femelle / Humains / Mâle Pays comme sujet: Amérique du Sud / Chili langue: Espagnol Texte intégral: Rev. méd. Chile Thème du journal: Médicament Année: 2004 Type: Article Pays d'affiliation: Chili Institution/Pays d'affiliation: Hospital Barros Luco-Trudeau/CL / Universidad de Chile/CL

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Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Plasmaphérèse / Maladies du système nerveux Limites du sujet: Femelle / Humains / Mâle Pays comme sujet: Amérique du Sud / Chili langue: Espagnol Texte intégral: Rev. méd. Chile Thème du journal: Médicament Année: 2004 Type: Article Pays d'affiliation: Chili Institution/Pays d'affiliation: Hospital Barros Luco-Trudeau/CL / Universidad de Chile/CL