Naturally acquired immunity to Haemophilus influenzae type B in healthy Cuban children
Mem. Inst. Oswaldo Cruz
;
99(7): 687-689, Nov. 2004. tab
Article
Dans Anglais
| LILACS
| ID: lil-391595
RESUMO
We have evaluated the prevalence of antibody to immunogenicity of Haemophilus influenzae type b (Hib) in a group of 4 to 5 years old healthy children, who were too old to be included in the first vaccinated cohort when Hib vaccination begun in Cuba in 1999. Serum capsular polysaccharide specific IgG antibody concentrations were measured in 974 healthy children, between February and May 2002. The prevalence of Hib nasopharyngeal carriage was also estimated. The majority of children (99.7 percent) had more than 1 µg/ml of antibody. The preliminary report of the nasopharyngeal cultures was positive for H. influenzae in 16 children, but in only one was confirmed as Hib after serotyping (0.1 percent Hib nasopharyngeal carrier). These results provide evidence that in Cuba the natural active immunity to Hib can be acquired at an early age.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Polyosides bactériens
/
Immunoglobuline G
/
Haemophilus influenzae type B
/
Immunité innée
/
Anticorps antibactériens
Type d'étude:
Étude de prévalence
/
Facteurs de risque
Limites du sujet:
Enfant d'âge préscolaire
/
Humains
Pays comme sujet:
Caraïbes
/
Cuba
langue:
Anglais
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
Médecine tropicale
/
Parasitologie
Année:
2004
Type:
Article
Pays d'affiliation:
Cuba
Institution/Pays d'affiliation:
Instituto de Medicina Tropical Pedro Kourí/CU
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS