Prospective study on the prevention of vertical transmission of HIV in Campo Grande, Mato Grosso do Sul, Brazil, from 1996 to 2001
Braz. j. infect. dis
;
9(1)Feb. 2005. tab, graf
Article
Dans Anglais
| LILACS
| ID: lil-404304
RESUMO
This prospective study, involving 76 pregnant women infected with HIV, paired with their 79 exposed infants, was carried out between May 1996 and October 2001, at the Reference Department for Pregnant Women Infected with HIV in Campo Grande, Mato Grosso do Sul. The mean age of the pregnant women was 24 years; 88 percent (67/76) apparently were infected due to sexual practices; 88 percent (67/76) were housewives; 823 percent (63/76) graduated from junior high school; 14.5 percent (11/76) reported co-infection with Hepatitis C, 9.2 percent with Syphilis; 51 percent (39/76) learned the diagnosis during prenatal care; 67 percent (51/76) reported HIV clinical symptomatology and 9.2 percent (7/76) reported opportunistic infections. Elective cesareans were performed in 57 percent (43/76). The mean gestational age at delivery was 38 weeks and we found 12.5 percent (10/80) pronatis; 97 percent (74/76) had a ruptured membrane time after less than four hours and one child (1.3 percent) was nursed. ACTG 076 Protocol (AIDS Clinical Trial Group 076) was used in 80 percent (61/76) of the pregnant women, with 100 percent adherence; 62 percent (38/61) used zidovudine plus another antiretroviral in the gestation; 92 percent (73/79) of the infants used zidovudine after the birth and 19 percent (14/73) used zidovudine and lamivudine. The transmission rate in this study was 2.5 percent.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Complications infectieuses de la grossesse
/
Infections à VIH
/
Transmission verticale de maladie infectieuse
/
Agents antiVIH
Type d'étude:
Essai clinique contrôlé
/
Etude diagnostique
/
Etude d'étiologie
/
Guide de pratique
/
Etude d'incidence
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adolescent
/
Adulte
/
Femelle
/
Humains
/
Nouveau-né
/
Grossesse
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Braz. j. infect. dis
Thème du journal:
Maladies transmissibles
Année:
2005
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Clementino Fraga Filho Hospital/BR
/
Federal University of Mato Grosso do Sul/BR
/
Infecto-Parasitic Center/BR
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