The use of naltrexone to treat ambulatory patients with alcohol dependence
Bol. Asoc. Méd. P. R
;
89(10/12): 157-160, Oct.-Dec. 1997.
Article
Dans Anglais
| LILACS
| ID: lil-411430
RESUMO
The purpose of this study is to evaluate the efficacy of Naltrexone in decreasing craving symptoms among Puerto Rican male veterans with alcohol dependence. METHOD:
This is a double blind placebo control study with a convenience sample of eleven patients divided in two groups (placebo and Naltrexone). Scales consisting of Zung Depression, Zung Anxiety, MMSE, OCD Screener, Craving, and Somatization were administered at baseline, and weekly for four weeks as follow up.RESULTS:
There were no statistically significant differences between the two groups on any of the outcome variables at baseline or follow up measurements. A statistical trend was noted toward a decrease in somatization. A decrease in craving symptoms was observed in the experimental group.CONCLUSIONS:
Even though our results did not show evidence of the efficacy of Naltrexone in decreasing craving symptoms, a small number of patients did benefit from the medication. The results could have been affected by the small sample size
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Indice:
LILAS (Amériques)
Sujet Principal:
Alcoolisme
/
Naltrexone
Type d'étude:
Essai clinique contrôlé
Limites du sujet:
Adulte
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Bol. Asoc. Méd. P. R
Thème du journal:
Médicament
Année:
1997
Type:
Article
Pays d'affiliation:
Porto Rico
Institution/Pays d'affiliation:
University of Puerto Rico/PR
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