Use of Cavia porcellus (Guinea Pigs) as an experimental model for Leishmania (Viannia) braziliensis
J. venom. anim. toxins incl. trop. dis
;
11(4): 605-609, out.-dez. 2005.
Article
Dans Anglais
| LILACS
| ID: lil-417730
RESUMO
Laboratory animals are fundamental to study immunological aspects and the efficacy of new drugs to treat leishmaniasis. However, we do not have practical and good animal models to study leishmaniasis caused by Leishmania (Viannia) braziliensis - L(V)b. In this study, thirty-two experimental animals (Cavia porcellus) were injected in the hind foot with 3x105 promastigote forms of L(V)b. The animals were followed for eight weeks. None of the experimental animals developed lesions or presented the parasite in any of the tests performed (histopathological exam, smears, culture, inoculation in hamsters, and polymerase chain reaction)
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Leishmania brasiliensis
/
Cochons d'Inde
Limites du sujet:
Animaux
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
J. venom. anim. toxins incl. trop. dis
Thème du journal:
Toxicologie
Année:
2005
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
University of Brasília/BR
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