Vasculitis ANCA-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: Report of four cases / Antineutrophil cytoplasmic antibody (ANCA)-positive vasculitis associated to the use of propylthiouracil
Rev. méd. Chile
;
134(4): 475-480, abr. 2006. ilus, tab
Article
Dans Espagnol
| LILACS
| ID: lil-428548
RESUMO
Antineutrophil cytoplasmic antibody (ANCA)-positive vasculitis is an uncommon complication of the use of propylthiouracil. When it occurs, it affects multiple organs as any systemic vasculitis. We report three females and one male, aged 30, 40, 43 and 41 years respectively, that after a lapse of 12 to 28 months of propylthiouracil use, presented clinical signs of vasculitis. All had high titers of ANCA against myeloperoxidase. In three patients, a skin biopsy confirmed the diagnosis. The condition subsided when propylthiouracil was discontinued, but one female patient required the use of prednisone.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Propylthiouracile
/
Antithyroïdiens
/
Vascularite
/
Anticorps anti-cytoplasme des polynucléaires neutrophiles
Type d'étude:
Facteurs de risque
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Mâle
langue:
Espagnol
Texte intégral:
Rev. méd. Chile
Thème du journal:
Médicament
Année:
2006
Type:
Article
Pays d'affiliation:
Chili
Institution/Pays d'affiliation:
Hospital Clínico San Borja Arriarán/CL
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS