Las lesiones placentarias en la infección humana por Trypanosoma cruzi / Placental lesions in human Trypanosoma cruzi infection
Rev. Soc. Bras. Med. Trop
;
38(supl.2): 84-86, 2005. ilus
Article
Dans Espagnol
| LILACS
| ID: lil-444169
ABSTRACT
This histopathological study analyzes placentas of babies congenitally infected with T. cruzi (M+B+), or babies not infected but born from infected- (M+B-), or non infected-mothers (M-B-). Placentas M+B+ showed lesions of chorionitis, chorioamnionitis and cord edema with lymphocyte infiltration, whereas such lesions were infiltrated only with polymorphonuclear cells in M+B- and M-B- placentas. Parasites were found in M+B+ placentas, in fibroblasts and macrophages of chorion, membranes, chorionic plate, mainly in the area of membrane insertion, as well as in cells of Wharton jelly and myocytes of umbilical cord vessels. These results suggest that the materno-fetal transmission of parasites occurs mainly through the marginal sinus, spreading into the chorionic plate infecting fibroblasts and macrophages so far as to found a fetal vessel, inducing a fetal infection by hematogenous route.
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Indice:
LILAS (Amériques)
Sujet Principal:
Placenta
/
Trypanosoma cruzi
/
Chorioamnionite
/
Maladie de Chagas
/
Complications parasitaires de la grossesse
/
Transmission verticale de maladie infectieuse
Limites du sujet:
Animaux
/
Femelle
/
Humains
/
Grossesse
langue:
Espagnol
Texte intégral:
Rev. Soc. Bras. Med. Trop
Thème du journal:
Médecine tropicale
Année:
2005
Type:
Article
/
Congrès et conférence
Pays d'affiliation:
Belgique
/
Bolivie
Institution/Pays d'affiliation:
ULB/BE
/
Universidad Mayor de San Simón (UMSS)/BO
/
Université Livre de Bruxelles/BE
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