Dosificación de anticuerpos IgM e IgA anti-trypanosoma cruzi en sangre de recién nacidos de madres con serología positiva para Chagas / Serum levels for IgM and IgA antibodies to anti-trypanosoma cruzi in samples of blood from newborns from mothers with positive serology for Chagas disease
Rev. Soc. Bras. Med. Trop
;
38(supl.2): 62-64, 2005. graf, tab
Article
Dans Espagnol
| LILACS
| ID: lil-444174
ABSTRACT
This study compares the levels of specific antibodies IgM and IgA for Chagas in samples of blood from newborns. Three groups of cord blood samples have been analysed a group of 42 samples from newborns, displaying positive parasitemia, of seropositive mothers (M+B+), 68 samples from newborns with negative parasitemia whose mothers were seropositive (M+B-) and a group of 45 control newborns coming from mothers with negative serology for Chagas. From the 42 M+B+ samples with congenital Chagas disease, 81 and 82.9% displayed detectable levels of IgM and IgA antibodies, respectively In the M+B- group, 70.6 and 33.8% presented antibodies of IgM and IgA classes, respectively, whereas in the control group M-B-, we detected 6% and 11.1% of IgM and IgA antibodies, respectively. The calculated sensitivity of detection of congenital cases using IgM or IgA antibodies was of 82.9% and 80.9% respectively, whereas the specificity of detection was of 29.4% for IgM antibodies and of 66.1% for IgA antibodies.
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Indice:
LILAS (Amériques)
Sujet Principal:
Trypanosoma cruzi
/
Immunoglobuline A
/
Immunoglobuline M
/
Maladie de Chagas
Type d'étude:
Etude diagnostique
/
Étude observationnelle
Limites du sujet:
Animaux
/
Humains
langue:
Espagnol
Texte intégral:
Rev. Soc. Bras. Med. Trop
Thème du journal:
Médecine tropicale
Année:
2005
Type:
Article
/
Congrès et conférence
Pays d'affiliation:
Belgique
/
Bolivie
Institution/Pays d'affiliation:
Universidad Mayor de San Simón (UMSS)/BO
/
Université Livre de Bruxelles/BE
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