Estimación de la parasitemia en la infección humana por Trypanosoma cruzi: las altas parasitemias están asociadas con la severa y fatal enfermedad de Chagas congenita / Estimation of the parasitemia in Trypanosoma cruzi human infection: high parasitemias are associated with severe and fatal congenital Chagas disease
Rev. Soc. Bras. Med. Trop
;
38(supl.2): 58-61, 2005. graf, tab, ilus
Article
Dans Espagnol
| LILACS
| ID: lil-444175
ABSTRACT
The aim of this study was to validate the method of microhematocrit tube, as a rapid method to estimate the parasitemia in blood and to associate the parasites concentration with the morbidity and mortality of new born children with congenital Chagas diseases. Our results were determined experimentally and shown that the detection limit of the microhematocrit tube method is 40 parasites/ml when at least one of the four observed tubes is positive. Besides, it was also established that when the four examined tubes are positive the parasitemia in blood reaches more than 100 parasites/ml. It is important to highlight the modification made by our laboratory in the microscopic observation of the microhematocrit tubes with respect to the methodology used by previous investigators. A positive association exists between a high number of parasites in blood and the morbi-mortality of the newly born children with congenital chagas. The results of positive association between the parasitic load and the morbility and mortality could constitute an argument to understand the possible role of the parasite in the pathology of the disease.
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Indice:
LILAS (Amériques)
Sujet Principal:
Numération des oeufs de parasites
/
Trypanosoma cruzi
/
Maladie de Chagas
/
Parasitémie
Type d'étude:
Etude diagnostique
/
Facteurs de risque
Limites du sujet:
Animaux
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Bolivie
langue:
Espagnol
Texte intégral:
Rev. Soc. Bras. Med. Trop
Thème du journal:
Médecine tropicale
Année:
2005
Type:
Article
/
Congrès et conférence
Pays d'affiliation:
Belgique
/
Bolivie
Institution/Pays d'affiliation:
Universidad Mayor de San Simón (UMSS)/BO
/
Université Livre de Bruxelles/BE
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