Phytochemical study and antiulcerogenic activity of Syngonanthus bisulcatus (Eriocaulaceae)
RBCF, Rev. bras. ciênc. farm. (Impr.)
;
42(3): 413-417, jul.-set. 2006. ilus, tab
Article
Dans Anglais
| LILACS
| ID: lil-446361
ABSTRACT
From the ethanol extract of the capitula and scapes of Syngonanthus bisulcatus (Koern) Ruhland the flavonoids 5-hydroxy-7,4'-dimethoxy-6-C-beta-D-glucopyranosylflavone, isovitexin (5,7,4'-trihydroxy-6-C-beta-D-glucopyranosylflavone), luteolin (5,7,3',4'-tetrahydroxyflavone), lutonarin (5,3',4'-trihydroxy-6-C-7-O-beta-D-glucopyranosylflavone) and 5,6,3',4'-tetrahydroxy-7-O-beta-D-glucopyrade were isolated. The structure of the compounds were characterized by spectroscopic methods, mainly 1D and 2D NMR experiments, as well as ESMS spectrometry. In addition we examined the effect of the ethanol extract of capitulae and scapes in the ulcer model ethanol/HCl-induced gastric mucosal lesions.
RESUMO
Do extrato etanólico dos capítulos e dos escapos de Syngonanthus bisulcatus (Koern) Ruhland foram isolados os flavonóides 5-hidroxi-7,4'-dimetoxi-6-C-beta-D-glicopiranosilflavona, isovitexina (5,7,4'-triidróxi-6-C-beta-D-glicopiranosilflavona, luteolina (5,7,3',4'- tetraidroxiflavona), lutonarina (5,3',4'-triidroxi-6-C-7-O-beta-D-glicopiranosilflavona) e 5,6,3',4'-tetraidroxi-7-O-beta-D-glicopiranosilflavona. As estruturas dos compostos foram caracterizadas por espectroscopia (RMN mono e bi-dimensionais) e por espectrometria de massas Electrospray. Adicionalmente foram examinados os efeitos dos extratos etanólicos dos capítulos e dos escapos pelo modelo de úlcera induzida por etanol/HCl
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Extraits de plantes
/
Eriocaulaceae
langue:
Anglais
Texte intégral:
RBCF, Rev. bras. ciênc. farm. (Impr.)
Thème du journal:
Biochimie
/
Pharmacie
/
Pharmacologie
Année:
2006
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
UNESP/BR
/
UNICAMP/BR
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