Gene Class expression: analysis tool of Gene Ontology terms with gene expression data
Genet. mol. res. (Online)
;
5(1): 108-114, Mar. 31, 2006. ilus
Article
Dans Anglais
| LILACS
| ID: lil-449141
ABSTRACT
Serial analysis of gene expression (SAGE) technology produces large sets of interesting genes that are difficult to analyze directly. Bioinformatics tools are needed to interpret the functional information in these gene sets. We present an interactive web-based tool, called Gene Class, which allows functional annotation of SAGE data using the Gene Ontology (GO) database. This tool performs searches in the GO database for each SAGE tag, making associations in the selected GO category for a level selected in the hierarchy. This system provides user-friendly data navigation and visualization for mapping SAGE data onto the gene ontology structure. This tool also provides graphical visualization of the percentage of SAGE tags in each GO category, along with confidence intervals and hypothesis testing.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Logiciel
/
Terminologie
/
Étiquettes de séquences exprimées
/
Analyse de profil d'expression de gènes
/
Bases de données génétiques
Type d'étude:
Facteurs de risque
Limites du sujet:
Animaux
/
Humains
langue:
Anglais
Texte intégral:
Genet. mol. res. (Online)
Thème du journal:
Biologie moléculaire
/
Génétique
Année:
2006
Type:
Article
Pays d'affiliation:
Argentine
/
Brésil
Institution/Pays d'affiliation:
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto/BR
/
USP/BR
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