The time has come: a new scene for PKU treatment
Genet. mol. res. (Online)
;
5(1): 33-44, Mar. 31, 2006. tab, ilus
Article
Dans Anglais
| LILACS
| ID: lil-449148
ABSTRACT
Phenylketonuria (PKU) is one of the few genetic diseases in which mental retardation can be prevented. Hence, diagnosis and treatment must be established early. PKU treatment consists of a phenylalanine-restricted diet supplemented with a phenylalanine-free mixture of amino acids. However, it is difficult to adhere to this diet. In the last decade, a better comprehension of the biochemistry, genetics and molecular basis of the disease, as well as the need for easier treatment, led to the development of several new therapeutic strategies for PKU. In the present study, we evaluated these new therapeutic options in terms of theoretical basis, methodologies, efficacy, and costs.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Phenylalanine 4-monooxygenase
/
Phénylcétonuries
/
Aliment formulé
/
Régime pauvre en protéines
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Genet. mol. res. (Online)
Thème du journal:
Biologie moléculaire
/
Génétique
Année:
2006
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade Federal de Minas Gerais/BR
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS