Perspectives in the control of infectious diseases by transgenic mosquitoes in the post-genomic era: a review
Mem. Inst. Oswaldo Cruz
;
102(4): 425-433, June 2007.
Article
Dans Anglais
| LILACS
| ID: lil-454803
ABSTRACT
Arthropod-borne diseases caused by a variety of microorganisms such as dengue virus and malaria parasites afflict billions of people worldwide imposing major economic and social burdens. Despite many efforts, vaccines against diseases transmitted by mosquitoes, with the exception of yellow fever, are not available. Control of such infectious pathogens is mainly performed by vector management and treatment of affected individuals with drugs. However, the numbers of insecticide-resistant insects and drug-resistant parasites are increasing. Therefore, inspired in recent years by a lot of new data produced by genomics and post-genomics research, several scientific groups have been working on different strategies to control infectious arthropod-borne diseases. This review focuses on recent advances and perspectives towards construction of transgenic mosquitoes refractory to malaria parasites and dengue virus transmission.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Animal génétiquement modifié
/
Lutte contre les moustiques
/
Vecteurs insectes
/
Culicidae
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
Médecine tropicale
/
Parasitologie
Année:
2007
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Faculdade de Medicina de Marília/BR
/
Universidade de São Paulo/BR
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