Avaliação laboratorial da toxicidade molecular em eritrócitos talassêmicos / Laboratorial evaluation of molecular toxicity in thalassemic erythrocytes
Rev. bras. hematol. hemoter
; 28(4): 301-302, out.-dez. 2006. ilus, tab
Article
Dans Pt
| LILACS
| ID: lil-456243
Responsable en Bibliothèque :
BR408.1
ABSTRACT
Oxygen-derived free radical damage is associated with the molecular toxicity of hemoglobin. Especially in thalassemia syndromes, this toxicity has a relationship with "free" alpha globin concentrations. This study of beta thalassemia trait blood samples from 39 individuals shows that the evaluation of methemoglobin is a sensitive method of indicating molecular toxicity and the superoxide dismutase concentration revealing the intensity of oxidative stress of this process.
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Thalassémie
/
Bêta-Thalassémie
/
Techniques de laboratoire clinique
/
Érythrocytes
Type d'étude:
Diagnostic_studies
Limites du sujet:
Humans
langue:
Pt
Texte intégral:
Rev. bras. hematol. hemoter
Thème du journal:
HEMATOLOGIA
Année:
2006
Type:
Article