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Avaliação laboratorial da toxicidade molecular em eritrócitos talassêmicos / Laboratorial evaluation of molecular toxicity in thalassemic erythrocytes
Naoum, Paulo Cesar; Querino, Sheldon S. S; Cury, Nathália M; Toledo, Cristiane G; Naoum, Flávio Augusto.
  • Naoum, Paulo Cesar; Academia de Ciência e Tecnologia de São José do Rio Preto. São José do Rio Preto. BR
  • Querino, Sheldon S. S; Academia de Ciência e Tecnologia de São José do Rio Preto. São José do Rio Preto. BR
  • Cury, Nathália M; Academia de Ciência e Tecnologia de São José do Rio Preto. São José do Rio Preto. BR
  • Toledo, Cristiane G; Academia de Ciência e Tecnologia de São José do Rio Preto. São José do Rio Preto. BR
  • Naoum, Flávio Augusto; Academia de Ciência e Tecnologia de São José do Rio Preto. São José do Rio Preto. BR
Rev. bras. hematol. hemoter ; 28(4): 301-302, out.-dez. 2006. ilus, tab
Article Dans Pt | LILACS | ID: lil-456243
Responsable en Bibliothèque : BR408.1
ABSTRACT
Oxygen-derived free radical damage is associated with the molecular toxicity of hemoglobin. Especially in thalassemia syndromes, this toxicity has a relationship with "free" alpha globin concentrations. This study of beta thalassemia trait blood samples from 39 individuals shows that the evaluation of methemoglobin is a sensitive method of indicating molecular toxicity and the superoxide dismutase concentration revealing the intensity of oxidative stress of this process.
Sujets)
Texte intégral: 1 Indice: LILACS Sujet Principal: Thalassémie / Bêta-Thalassémie / Techniques de laboratoire clinique / Érythrocytes Type d'étude: Diagnostic_studies Limites du sujet: Humans langue: Pt Texte intégral: Rev. bras. hematol. hemoter Thème du journal: HEMATOLOGIA Année: 2006 Type: Article
Texte intégral: 1 Indice: LILACS Sujet Principal: Thalassémie / Bêta-Thalassémie / Techniques de laboratoire clinique / Érythrocytes Type d'étude: Diagnostic_studies Limites du sujet: Humans langue: Pt Texte intégral: Rev. bras. hematol. hemoter Thème du journal: HEMATOLOGIA Année: 2006 Type: Article