Vasculonecrotic reactions in leprosy
Braz. j. infect. dis
;
11(3): 378-382, June 2007. tab, ilus
Article
Dans Anglais
| LILACS
| ID: lil-457642
ABSTRACT
Multibacillary, lepromatous or borderline leprosy patients may present two types of vasculonecrotic reactions Lucio phenomenon and that associated with erythema nodosum leprosum. Despite they can be distinguished through clinical and histological characteristics; both are often used as synonyms. It is said that leprosy reaction should be properly classified for therapeutic reasons, since it is well known that in Lucio phenomenon there is not a good response to thalidomide. The authors reported two cases of vasculonecrotic phenomena in lepromatous leprosy sharing clinical and histopathological characteristics of both reaction subtypes. The findings may indicate the spectral nature of the reaction phenomena in leprosy and emphasize the importance of the clinic-pathological correlation for proper classification. Our findings may contribute to the understanding of leprosy reactions pathogenesis, broaden the knowledge about their outcome with standard treatment, and provide the scientific background to design better therapeutic strategies for these complications.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Lèpre lépromateuse
/
Vascularite leucocytoclasique cutanée
/
Érythème noueux
/
Antilépreux
Limites du sujet:
Adolescent
/
Adulte
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Braz. j. infect. dis
Thème du journal:
Maladies transmissibles
Année:
2007
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
State University of Campinas/BR
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