Low sensitivity of polymerase chain reaction for diagnosis of tuberculous meningitis in southeastern Brazil
Rev. Soc. Bras. Med. Trop
; 34(4): 389-393, jul.-ago. 2001. tab
Article
Dans En
| LILACS
| ID: lil-461925
Responsable en Bibliothèque :
BR1.1
ABSTRACT
Two polymerase chain reaction (PCR) protocols showed low sensitivity (36% and 53% for TB AMPLICOR and MPB64 nested PCR, respectively), when compared with classic microbiological methods (73% and 54% for Ziehl-Neelsen staining and culture, respectively), in the diagnosis of tuberculous meningitis in 91 patients in southeastern Brazil. Only three PCR-positive, microbiologically negative patients were found. Analysis of sequential cerebrospinal fluid samples by nested PCR detected Mycobacterium tuberculosis DNA up to 29 days after the introduction of antituberculosis chemotherapy.
RESUMO
Exames coproparasitológicos realizados em 191 crianças de creches e em 434 alunos da primeira à quarta série das áreas urbana e rural da rede municipal de Rolândia, PR, evidenciaram enteroparasitas em prevalência de 15,2% nas creches e de 52,5% entre os escolares. Fatores de risco são discutidos.
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Méningite tuberculeuse
/
Réaction de polymérisation en chaîne
Type d'étude:
Diagnostic_studies
/
Guideline
/
Observational_studies
/
Risk_factors_studies
Limites du sujet:
Humans
Pays comme sujet:
America do sul
/
Brasil
langue:
En
Texte intégral:
Rev. Soc. Bras. Med. Trop
Thème du journal:
MEDICINA TROPICAL
Année:
2001
Type:
Article