Does the use of paclitaxel or rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent?
São Paulo med. j
;
125(4): 242-245, July 2007. tab
Article
Dans Anglais
| LILACS
| ID: lil-467136
ABSTRACT
CONTEXT AND OBJECTIVE:
The safety and efficacy of drug-eluting stents reduce the need for surgical revascularization. The objective of the present study was to investigate whether paclitaxel or rapamycin-eluting stent are effective in avoiding the need for coronary-artery bypass grafting.METHODS:
This was a systematic review of the literature using the methodology of the Cochrane Collaboration. The type of study considered was controlled randomized trials; the type of intervention was drug-eluting or bare-metal stents; and the main outcome investigated was coronary-artery bypass grafting.RESULTS:
The ten studies included in this systematic review did not show any statistically significant difference between the drug-eluting stents and the bare-metal stents with regard to the outcome of coronary-artery bypass grafting (confidence interval 0.31 to 1.42).CONCLUSION:
The surgical revascularization rate was not reduced by the use of drug-eluting stents.RESUMO
CONTEXTO E OBJETIVO:
A segurança e eficácia dos stents recobertos com drogas reduz a necessidade da cirurgia de revascularização cardíaca. O objetivo foi verificar se os stents recobertos com paclitaxel ou rapamicina são efetivos para evitar a necessidade de revascularização cirúrgica das coronárias.MÉTODOS:
Revisão sistemática da literatura usando a metodologia do Centro Cochrane. Tipos de estudos estudos clínicos randomizados; tipo de intervenção stents recobertos com drogas ou stents convencionais; desfecho principal cirurgia de revascularização cardíaca.RESULTADOS:
Os 10 estudos incluídos nesta revisão sistemática não mostram diferença estatisticamente significante entre os stents recobertos com drogas e os stents convencionais no desfecho principal, com intervalo de confiança de 0.31, 1.42.CONCLUSÃO:
A taxa de revascularização cardíaca não é reduzida pelo uso de stents recobertos com drogas.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Endoprothèses
/
Pontage aortocoronarien
/
Paclitaxel
/
Sirolimus
/
Resténose coronaire
/
Cytostatiques
Type d'étude:
Essai clinique contrôlé
/
Revues systématiques évaluées
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
São Paulo med. j
Thème du journal:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Médicament
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Année:
2007
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Brazilian Cochrane Center/BR
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