Retrospective study comparing six - and twelve-core prostate biopsy in detection of prostate cancer
Int. braz. j. urol
;
34(1): 9-14, Jan.-Feb. 2008. tab
Article
Dans Anglais
| LILACS
| ID: lil-482937
ABSTRACT
OBJECTIVE:
We compared the safety and efficacy of the 12-core biopsy with those of the conventional systematic 6-core biopsy with PSA levels between 4.1 and 20.0 ng/mL. MATERIALS ANDMETHODS:
This study included 428 patients who underwent a 6-core biopsy and 128 patients who underwent a 12-core biopsy. Biopsies were performed transrectally under ultrasound guidance. The 12-core biopsy scheme involved obtaining 6 far lateral cores.RESULTS:
For patients with PSA level between 4.1 and 10.1 ng/mL, 47 of the 265 patients who underwent 6-core biopsy and 32 of the 91 patients who underwent a12-core biopsy were diagnosed with prostate cancer (p = 0.0006). Among the patients with a PSA level between 10.1 and 20.0 ng/mL, 48 of 163 patients who underwent the 6-core biopsy and 16 of 37 patients who underwent the 12-core biopsy were diagnosed with prostate cancer (p = 0.0606). Three of the 95 patients who were diagnosed with prostate cancer through the 6-core biopsy and 12 of the 48 patients who were diagnosed through the 12-core biopsy had cancer located in the anterior apex. The 12-core biopsy increased the diagnostic rate in the apex (p = 0.001). No statistically significant differences were found in incidence of complications.CONCLUSION:
We concluded that the 12-core biopsy is a safe and more effective procedure for increasing the diagnostic rate of prostate cancer than the 6-core biopsy in patients with PSA level between 4.1 and 10.0 ng/mL, and the most useful anatomical area to be added was found to be cores from the anterior apex.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Prostate
/
Tumeurs de la prostate
/
Ponction-biopsie à l'aiguille
Type d'étude:
Etude diagnostique
/
Guide de pratique
/
Étude observationnelle
/
Facteurs de risque
Limites du sujet:
Adulte très âgé
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Int. braz. j. urol
Thème du journal:
Urologie
Année:
2008
Type:
Article
Pays d'affiliation:
Japon
Institution/Pays d'affiliation:
Aichi Medical University/JP
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