Función renal en cirugía cardíaca con circulación extracorpórea: Pacientes valvulares y coronarios / Renal function during cardiac surgery with extracorporeal circulation
Rev. méd. Chile
;
136(4): 459-466, abr. 2008. graf, tab
Article
Dans Espagnol
| LILACS
| ID: lil-484921
ABSTRACT
Background:
Patients with valvular heart disease are at high risk of acute renal failure after surgery with extracorporeal circulation.Aim:
To describe changes in renal function parameters during surgery with extracorporeal circulation in patients with valvular heart disease and compare them with those found in patients undergoing elective coronary surgery Material andMethods:
Two groups of patients were studied. Group 1 was composed by twelve patients undergoing elective coronary surgery and group 2 was composed by eleven patients undergoing surgery for heart valve replacement. Glomerular filtration rate and effective renal plasma now were estimated from inulin and the 131 I-hippuran clearance respectively, at five different times, during surgery and the postoperative period. Sodium filtration fraction and fractional excretion were calculated. Alpha and pi-glutathione s-transferase in urine were measured as markers of tubular damage in the pre and postoperative periods.Results:
Effective renal plasma flow was reduced in both groups before induction of anesthesia, did not change during surgery and decreased significantly in patients with valvular disease in the postoperative period. Glomerular filtration rates were normal during all the study period. There was a non significant reduction of filtration fraction during extracorporeal circulation. Alpha and pi glutathione s-transferases were normal and did not change. Fractional excretion of sodium increased significantly postoperativelyConclusions:
In patients with valvular disease undergoing surgery with extracorporeal circulation, renal function does not deteriorate. No significant difference was found when compared with patients undergoing coronary surgery. No evidence of functional and cellular renal disfunction or damage was found in both study groups.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Circulation extracorporelle
/
Procédures de chirurgie cardiaque
/
Valvulopathies
/
Rein
/
Tests de la fonction rénale
Type d'étude:
Étude observationnelle
/
Facteurs de risque
Limites du sujet:
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Espagnol
Texte intégral:
Rev. méd. Chile
Thème du journal:
Médicament
Année:
2008
Type:
Article
/
descriptif de projet
Pays d'affiliation:
Chili
Institution/Pays d'affiliation:
Pontificia Universidad Católica de Chile/CL
/
Universidad Santo Tomás/CL
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