Urban transmission of Chagas disease in Cochabamba, Bolivia
Mem. Inst. Oswaldo Cruz
;
103(5): 423-430, Aug. 2008. ilus, tab
Article
Dans Anglais
| LILACS
| ID: lil-491961
ABSTRACT
Chagas disease is a major public health problem in Bolivia. In the city of Cochabamba, 58 percent of the population lives in peripheral urban districts ("popular zones") where the infection prevalence is extremely high. From 1995 to 1999, we studied the demographics of Chagas infections in children from five to 13 years old (n = 2218) from the South zone (SZ) and North zone (NZ) districts, which differ in social, environmental, and agricultural conditions. Information gathered from these districts demonstrates qualitative and quantitative evidence for the active transmission of Trypanosoma cruzi in urban Cochabamba. Seropositivity was high in both zones (25 percent in SZ and 19 percent in NZ). We observed a high risk of infection in children from five to nine years old in SZ, but in NZ, a higher risk occurred in children aged 10-13, with odds ratio for infection three times higher in NZ than in SZ. This difference was not due to triatomine density, since more than 1,000 Triatoma infestans were captured in both zones, but was possibly secondary to the vector infection rate (79 percent in SZ and 37 percent in NZ). Electrocardiogram abnormalities were found to be prevalent in children and pre-adolescents (SZ = 40 percent, NZ = 17 percent), indicating that under continuous exposure to infection and re-infection, a severe form of the disease may develop early in life. This work demonstrates that T. cruzi infection should also be considered an urban health problem and is not restricted to the rural areas and small villages of Bolivia.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Triatoma
/
Trypanosoma cruzi
/
Connaissances, attitudes et pratiques en santé
/
Maladie de Chagas
/
Vecteurs insectes
Type d'étude:
Etude diagnostique
/
Etude d'étiologie
/
Étude de prévalence
/
Recherche qualitative
/
Facteurs de risque
Limites du sujet:
Animaux
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Bolivie
langue:
Anglais
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
Médecine tropicale
/
Parasitologie
Année:
2008
Type:
Article
Pays d'affiliation:
Bolivie
/
Brésil
Institution/Pays d'affiliation:
Fiocruz/BR
/
Universidad Mayor de San Simón/BO
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