Preparation and characterisation of ethylcellulose microparticles containing propolis
Rev. ciênc. farm. básica apl
;
29(2): 129-134, 2008. tab, ilus, graf
Article
Dans Anglais
| LILACS
| ID: lil-514281
ABSTRACT
Ethylcellulose microparticles containing propolis ethanolic extract (PE) were prepared by the emulsification and solvent evaporation method. Three ratios of ethylcellulose to PE dry residue value (DR) weretested (10.25, 14 and 110). Moreover, polysorbate 80 was used as emulsifier in the external phase (1.0 or 1.5% w/w). Regular particle morphology without amorphous and/or sticking characteristics was achieved only when an ethylcellulose DR ratio of 10.25 and 1.0% polysorbate 80 were used. Microparticles had a mean diameter of 85.83 mium. The entrapment efficiency forpropolis of the microparticles was 62.99 more or less 0.52%. These ethylcellulose microparticles containing propolis would be useful for developing propolis aqueous dosage forms without the strong and unpleasant taste, aromatic odour and high ethanol concentration of PE.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Propolis
/
Éthanol
langue:
Anglais
Texte intégral:
Rev. ciênc. farm. básica apl
Thème du journal:
Pharmacologie
Année:
2008
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
State University of Maringa/BR
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