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The role of fecal calprotectin in investigating inflammatory bowel diseases
Erbayrak, Mustafa; Turkay, Cansel; Eraslan, Elife; Cetinkaya, Hulya; Kasapoglu, Benan; Bektas, Mehmet.
  • Erbayrak, Mustafa; Fatih University Hospital. Gastroenterology Department. Ankara. TR
  • Turkay, Cansel; Fatih University Hospital. Gastroenterology Department. Ankara. TR
  • Eraslan, Elife; Fatih University Hospital. Gastroenterology Department. Ankara. TR
  • Cetinkaya, Hulya; Ankara University Hospital. Gastroenterology Department. Ankara. TR
  • Kasapoglu, Benan; Fatih University Hospital. Internal Medicine Department. Ankara. TR
  • Bektas, Mehmet; Ankara University Hospital. Gastroenterology Department. Ankara. TR
Clinics ; 64(5): 421-425, 2009. tab
Article Dans Anglais | LILACS | ID: lil-514754
ABSTRACT

INTRODUCTION:

Invasive and non-invasive tests can be used to evaluate the activity of inflammatory bowel diseases.

OBJECTIVE:

The aim of the present study was to investigate the role of fecal calprotectin in evaluating inflammatory bowel disease activity and the correlation of fecal calprotectin with the erythrocyte sedimentation rate and C reactive protein values in inflammatory bowel disease.

METHOD:

Sixty-five patients affected with inflammatory bowel disease were enrolled. Twenty outpatients diagnosed with inflammatory bowel disease comprised the control group.

RESULTS:

In the present study, all patients in the control group had an fecal calprotectin value lower than the cut-off point (50 mg/kg).

CONCLUSION:

In conclusion, fecal calprotectin was found to be strongly associated with colorectal inflammation indicating organic disease. Fecal calprotectin is a simple and non-invasive method for assessing excretion of macrophages into the gut lumen. Fecal calprotectin values can be used to evaluate the response to treatment, to screen asymptomatic patients, and to predict inflammatory bowel disease relapses.
Sujets)

Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Maladies inflammatoires intestinales / Complexe antigénique L1 leucocytaire / Fèces Type d'étude: Essai clinique contrôlé / Étude observationnelle / Étude pronostique / Facteurs de risque Limites du sujet: Adulte / Adulte très âgé / Femelle / Humains / Mâle langue: Anglais Texte intégral: Clinics Thème du journal: Médicament Année: 2009 Type: Article Pays d'affiliation: Turquie Institution/Pays d'affiliation: Ankara University Hospital/TR / Fatih University Hospital/TR

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Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Maladies inflammatoires intestinales / Complexe antigénique L1 leucocytaire / Fèces Type d'étude: Essai clinique contrôlé / Étude observationnelle / Étude pronostique / Facteurs de risque Limites du sujet: Adulte / Adulte très âgé / Femelle / Humains / Mâle langue: Anglais Texte intégral: Clinics Thème du journal: Médicament Année: 2009 Type: Article Pays d'affiliation: Turquie Institution/Pays d'affiliation: Ankara University Hospital/TR / Fatih University Hospital/TR