The role of fecal calprotectin in investigating inflammatory bowel diseases
Clinics
;
64(5): 421-425, 2009. tab
Article
Dans Anglais
| LILACS
| ID: lil-514754
ABSTRACT
INTRODUCTION:
Invasive and non-invasive tests can be used to evaluate the activity of inflammatory bowel diseases.OBJECTIVE:
The aim of the present study was to investigate the role of fecal calprotectin in evaluating inflammatory bowel disease activity and the correlation of fecal calprotectin with the erythrocyte sedimentation rate and C reactive protein values in inflammatory bowel disease.METHOD:
Sixty-five patients affected with inflammatory bowel disease were enrolled. Twenty outpatients diagnosed with inflammatory bowel disease comprised the control group.RESULTS:
In the present study, all patients in the control group had an fecal calprotectin value lower than the cut-off point (50 mg/kg).CONCLUSION:
In conclusion, fecal calprotectin was found to be strongly associated with colorectal inflammation indicating organic disease. Fecal calprotectin is a simple and non-invasive method for assessing excretion of macrophages into the gut lumen. Fecal calprotectin values can be used to evaluate the response to treatment, to screen asymptomatic patients, and to predict inflammatory bowel disease relapses.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Maladies inflammatoires intestinales
/
Complexe antigénique L1 leucocytaire
/
Fèces
Type d'étude:
Essai clinique contrôlé
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Clinics
Thème du journal:
Médicament
Année:
2009
Type:
Article
Pays d'affiliation:
Turquie
Institution/Pays d'affiliation:
Ankara University Hospital/TR
/
Fatih University Hospital/TR
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