Long-term surgical outcomes of primary congenital glaucoma in China
Clinics
;
64(6): 543-551, June 2009. graf, tab
Article
Dans Anglais
| LILACS
| ID: lil-517935
ABSTRACT
OBJECTIVE:
To evaluate the long-term outcomes of three surgical procedures for the treatment of primary congenital glaucoma (PCG).INTRODUCTION:
PCG is one of the main causes of blindness in children. There is a paucity of contemporary data on PCG in China.METHODS:
A retrospective study of 48 patients (81 eyes) with PCG who underwent primary trabeculectomy, trabeculotomy, or combined trabeculotomy and trabeculectomy (CTT).RESULTS:
All patients were less than 4 years (yrs) of age, with a mean age of 2.08 ¡À 1.23 yrs. The mean duration of follow-up was 5.49 ¡À 3.09 yrs. The difference in success rates among the three surgical procedures at 1, 3, 6 and 9 yrs was not statistically significant (p = 0.492). However, in patients with over 4 yrs of follow-up, Kaplan-Meier survival analysis revealed that the success rates of trabeculectomy and CTT declined more slowly than that of trabeculotomy. Among the patients, 66.22% acquired good vision (VA ¡Ý 0.4), 17.57% acquired fair vision (VA = 0.1 - 0.3), and 16.22% acquired poor vision (VA < 0.1). The patients with good vision were mostly in the successful surgery group. Myopia was more prevalent postoperatively (p = 0.009). Reductions in the cup-disc ratio and corneal diameter were only seen in the successful surgery group (p = 0.000). In addition, the successful surgery group contained more patients that complied with a regular follow-up routine (p = 0.002).DISCUSSION:
Our cases were all primary surgeries. Primary trabeculectomy was performed in many cases because no treatment was sought until an advanced stage of disease had been reached.CONCLUSIONS:
In contrast to most reports, in the present study, trabeculectomy and CTT achieved higher long-term success rates than trabeculotomy. The patients with successful surgical results had better vision. Compliance with a routine of regular follow-up may increase the chances of a successful surgical outcome.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Trabéculectomie
/
Glaucome
Type d'étude:
Étude observationnelle
Limites du sujet:
Enfant
/
Enfant d'âge préscolaire
/
Humains
/
Bébé
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Clinics
Thème du journal:
Médicament
Année:
2009
Type:
Article
Pays d'affiliation:
Chine
Institution/Pays d'affiliation:
Sun Yat-sen University/CN
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