Trastorno linfoproliferativo post trasplante renal en un niño / Lymphoproliferative disorders after renal transplantation in a child
Rev. méd. Chile
; 137(3): 405-410, mar. 2009. ilus, tab
Article
de Es
| LILACS
| ID: lil-518502
Bibliothèque responsable:
BR1.1
ABSTRACT
Post transplant lymphoproliferative disorder (PTLD) is the commonest form of post transplant malignancy in children. The incidence in renal transplant recipients varies between 2 percent-4 percent. They are characterized by uncontrolled B lymphocyte proliferation, in most cases driven by Epstein Barr virus (EBV). They are more common in younger children, EBV seronegative patients and those who receive aggressive immunosuppression. PTLD commonly presents in an unspecific form and it requires high suspicion rate for its diagnosis, especially in children with risk factors. We report a twelve year-old girl who developed fever, sore throat and lymph node enlargement, six months after receiving a renal allograft. Laboratory assessment and imaging studies were compatible with PTLD, which was confirmed by biopsy. Treatment was reduction of immunosuppression and surveillance. The patient had a favorable evolution.
Mots clés
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Transplantation rénale
/
Sirolimus
/
Immunosuppresseurs
/
Syndromes lymphoprolifératifs
Type d'étude:
Risk_factors_studies
Limites du sujet:
Child
/
Female
/
Humans
langue:
Es
Texte intégral:
Rev. méd. Chile
Thème du journal:
MEDICINA
Année:
2009
Type:
Article