Nueva variante en el polimorfismo del intrón 4 de la enzima Oxido Nítrico Sintasa endotelial (eNOS) / A new variant of the polymorphism in the fourth intron from the endothelial nitric oxide synthase enzyme
Prensa méd. argent
;
95(5): 291-294, jul. 2008. ilus
Article
Dans Espagnol
| LILACS
| ID: lil-522001
ABSTRACT
Nitric oxide (NO) derived from endothelial Nitric Oxide Synthase enzyme (eNOS) is an important mediator of the vascular function. Various polymorphisms have been described for the eNOS gene that has effects on its expression. One of the most studied markers in the eNOS gen is located in the fourth intron and is characterized by the presence of a variable number of tandemly repeated sequence of 27 base pairs. In this work we report the existence and the sequence of a new variant for these polymorphism and we hypothestize its potential role in the regulation of NO productition by eNOS.
Recherche sur Google
Indice:
LILAS (Amériques)
Sujet Principal:
Polymorphisme génétique
/
Maladie des artères coronaires
/
Marqueurs génétiques
/
Ischémie myocardique
/
Séquences répétées en tandem
/
MicroARN
/
Allèles
/
Nitric oxide synthase type III
Limites du sujet:
Humains
langue:
Espagnol
Texte intégral:
Prensa méd. argent
Thème du journal:
Médicament
Année:
2008
Type:
Article
Pays d'affiliation:
Argentine
Institution/Pays d'affiliation:
Fundación Favaloro/AR
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS