Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios / Cystatin C and adiponectin in diabetics with and without coronary artery disease
Rev. méd. Chile
;
137(6): 729-736, jun. 2009. ilus, tab
Article
Dans Espagnol
| LILACS
| ID: lil-524951
ABSTRACT
Background:
Patients with type 2 diabetes have a high incidence of coronary artery disease, which is even higher among those with renal failure. A serum level of cystatin C are used to assess renal function and is a potential cardiovascular risk factor. Adiponectin is an anti-atherogenic factor.Aim:
To measure cystatin C and adiponectin in type 2 diabetic patients with and without coronary artery disease. Material andmethods:
Nine diabetic patients with coronary artery disease aged 76± 10 years, 20 diabetics without coronary artery disease aged 61 ±5 years and 20 non diabetic subjects aged 57±10 years, were studied.Results:
Serum levels of cystatin C (mg/L) were 1.5 (range 0.89-219), 0.81 (range 0.71-1.08) and 0.68 mg/L (range 055-0.75) in diabetics with and without coronary artery disease and controls, respectively (p <0.0001). No differences in adiponectin between groups and no association between cystatin C and adiponectin, were observed. No association between both parameters and body mass index orglycosilated hemoglobin Ale was observed. Cystatin C had a positive correlation with serum creatinine (r =0.57p <0.001).Conclusions:
Diabetics with coronary artery disease have higher levels of cystatin C, that are closely correlated with serum creatinine levels.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Maladie des artères coronaires
/
Angiopathies diabétiques
/
Adiponectine
/
Cystatine C
Type d'étude:
Etude d'étiologie
/
Étude observationnelle
/
Facteurs de risque
Limites du sujet:
Adulte très âgé
/
Humains
langue:
Espagnol
Texte intégral:
Rev. méd. Chile
Thème du journal:
Médicament
Année:
2009
Type:
Article
Pays d'affiliation:
Chili
Institution/Pays d'affiliation:
Hospital San Juan de Dios/CL
/
Universidad de Chile/CL
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