Influence of probiotics on Candida presence and IgA anti-Candida in the oral cavity
Braz. j. microbiol
;
40(4): 960-964, Oct.-Dec. 2009. graf
Article
Dans Anglais
| LILACS
| ID: lil-528181
ABSTRACT
Probiotics are defined as microorganisms that promote benefits to host health, mainly by regulating resident microbiota. Disequilibrium in microbiota can favor the growth of opportunist microorganisms and the development of pathologies, like candidosis caused by yeasts of the Candida genus. This work evaluated whether probiotics consumption was able to influence a specific immunological response to Candida and the presence of these yeasts in the oral cavity. Saliva samples were collected from healthy individuals and plated in Dextrose Saboraud Agar with chloramphenicol. Individuals presenting Candida in the oral cavity used the probiotic Yakult LBâ for 20 days, after which new collections and identifications were performed. Anti-Candida IgA analysis was conducted using the ELISA technique. Analysis of the results showed a significant reduction in Candida prevalence (46 percent) and mean Candida CFU/mL counts (65 percent). The Candida species identified were C. albicans (98 percent) and C.tropicalis (2 percent), before and after probiotics consumption. Immunological analysis demonstrated a significant reduction in anti-Candida IgA levels after probiotics use, probably due to less antigenic stimulation. In conclusion, in the individuals studied, probiotics use significantly reduced the amount of Candida in the oral cavity, possibly due to competition between the yeasts rather than by specific secretory immune response stimulation.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Bifidobacterium
/
Techniques in vitro
/
Candidose buccale
/
Immunoglobuline A
/
Immunité muqueuse
/
Probiotiques
/
Agar-agar
/
Infections à Bifidobacteriales
/
Lacticaseibacillus casei
Type d'étude:
Etude diagnostique
/
Études d'évaluation
/
Facteurs de risque
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Braz. j. microbiol
Thème du journal:
Microbiologie
Année:
2009
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade de Taubaté/BR
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