Postantibiotic effects and postantibiotic sub-MIC effects of tilmicosin, erythromycin and tiamulin on erythromycin-resistant Streptococcus suis
Braz. j. microbiol
;
40(4): 980-987, Oct.-Dec. 2009. tab
Article
Dans Anglais
| LILACS
| ID: lil-528188
ABSTRACT
The postantibiotic effects (PAEs) and postantibiotic sub-MIC effects (PA SMEs) of tilmicosin, erythromycin and tiamulin on erythromycin-susceptible and erythromycin-resistant strains of Streptococcus suis (M phenotype) were investigated in vitro. Tilmicosin and tiamulin induced significantly longer PAE and PA SME against both erythromycin-susceptible and erythromycin-resistant strains than did erythromycin. The durations of PAE and PA SMEs were proportional to the concentrations of drugs used for exposure. The PA SMEs were substantially longer than PAEs on S. suis (P<0.05) regardless of the antimicrobial used for exposure. The results indicated that the PAE and PA SME could help in the design of efficient control strategies for infection especially caused by erythromycin-resistant S. suis and that they may provide additional valuable information for the rational drug use in clinical practice.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Infections à streptocoques
/
Suidae
/
Techniques in vitro
/
Résistance microbienne aux médicaments
/
Streptococcus suis
/
Prédisposition aux maladies
/
Antibactériens
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Braz. j. microbiol
Thème du journal:
Microbiologie
Année:
2009
Type:
Article
Pays d'affiliation:
Chine
Institution/Pays d'affiliation:
Nanjing Agricultural University/CN
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS