Your browser doesn't support javascript.
loading
Comparative antiplaque and antigingivitis efficacy of three antiseptic mouthrinses: a two week randomized clinical trial
Amini, Pejmon; Araujo, Marcelo Werneck Barata; Wu, Mei-Miau; Charles, Christine Ann; Sharma, Naresh Chandera.
  • Amini, Pejmon; BioSci America. Las Vegas. US
  • Araujo, Marcelo Werneck Barata; Johnson & Johnson Consumer Companies. Morris Plains. US
  • Wu, Mei-Miau; Johnson & Johnson Consumer Companies. Morris Plains. US
  • Charles, Christine Ann; Johnson & Johnson Consumer Companies. Morris Plains. US
  • Sharma, Naresh Chandera; BioSci Canada. Mississauga. CA
Braz. oral res ; 23(3): 319-325, 2009. tab
Article Dans Anglais | LILACS | ID: lil-530271
ABSTRACT
The objective of this randomized, examiner blind, parallel group, controlled clinical trial was to compare the antiplaque and antigingivitis efficacy of an essential oil-containing mouthrinse (EO) to two mouthrinses containing 0.05 percent Cetylpyridinium Chloride (CPC), one with alcohol and one alcohol-free, using a two-week experimental gingivitis validated-model with a 5 percent hydroalcohol rinse serving as the negative control. One hundred and fifty-nine subjects, 56 males and 103 females; ranging in age from 18 to 58 years in good general health were assigned to one of the four treatment groups EO (n = 40), 0.05 percent CPC with alcohol (CPCa, n = 39), 0.05 percent CPC alcohol-free (CPCna, n = 40), and 5 percent hydroalcohol negative control (n = 40). The Mean Turesky Modification of the Quigley-Hein Plaque Index (PI) and the Mean Modified Gingival Index (MGI) were the primary efficacy endpoints and were evaluated at baseline and at two weeks. Following baseline examinations, subjects received a complete dental prophylaxis and began supervised rinsing with their assigned mouthrinse twice daily for two weeks, as their sole oral hygiene measure; 151 subjects completed the trial. Two weeks after baseline the EO adjusted mean PI and MGI scores were significantly lower than those of both CPC rinses and negative control (p < 0.001). In conclusion, the EO mouthrinse demonstrated significantly greater antiplaque and antigingivitis efficacy than both CPC-containing mouthrinses and the negative control.
Sujets)

Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Cétylpyridinium / Plaque dentaire / Gingivite / Anti-infectieux locaux / Bains de bouche Type d'étude: Essai clinique contrôlé / Étude pronostique Limites du sujet: Adolescent / Adulte / Femelle / Humains / Mâle langue: Anglais Texte intégral: Braz. oral res Thème du journal: Dentisterie Année: 2009 Type: Article Pays d'affiliation: Canada / États-Unis d'Amérique Institution/Pays d'affiliation: BioSci America/US / BioSci Canada/CA / Johnson & Johnson Consumer Companies/US

Documents relatifs à ce sujet

MEDLINE

...
LILACS

LIS

Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Cétylpyridinium / Plaque dentaire / Gingivite / Anti-infectieux locaux / Bains de bouche Type d'étude: Essai clinique contrôlé / Étude pronostique Limites du sujet: Adolescent / Adulte / Femelle / Humains / Mâle langue: Anglais Texte intégral: Braz. oral res Thème du journal: Dentisterie Année: 2009 Type: Article Pays d'affiliation: Canada / États-Unis d'Amérique Institution/Pays d'affiliation: BioSci America/US / BioSci Canada/CA / Johnson & Johnson Consumer Companies/US