Antimicrobial susceptibility of Streptococcus pneumoniae and genotypic characterization of erythromycin-resistant strains in Porto Alegre, Brazil
Braz. j. microbiol
;
41(1): 1-5, Jan.-Mar. 2010. tab
Article
Dans Anglais
| LILACS
| ID: lil-531725
ABSTRACT
The antimicrobial susceptibility of 64 strains of S. pneumoniae obtained from three hospitals in Porto Alegre, Brazil, isolated between 2004 and 2005, was determined, using the agar-dilution method. The prevalence of resistant (intermediate and full resistance) strains to trimethoprim/sulphamethoxazole, penicillin, tetracycline, erythromycin, chloramphenicol, and ceftriaxone were 68 percent, 28 percent, 18 percent, 15 percent, 3 percent, and 1 percent, respectively. All strains were susceptible to vancomycin. Among 18 penicillin-resistant strains, 7 were resistant to at least two other antimicrobial drugs. All erythromycin-resistant strains, except one, contained the erm(B) and/or mef(A/E) genes, with a predominance of the former. The resistance rate to penicillin and erythromycin in Porto Alegre remained stable. The combination of trimethoprim/ sulphamethoxazole should not be recommended to treat pneumococcal infections, because of the high rate of resistant strains.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Infections à pneumocoques
/
Streptococcus pneumoniae
/
Résistance aux substances
/
Prédisposition génétique à une maladie
Type d'étude:
Etude diagnostique
/
Facteurs de risque
Limites du sujet:
Humains
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Braz. j. microbiol
Thème du journal:
Microbiologie
Année:
2010
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Instituto de Ciências Básicas da Saúde/BR
/
Universidade Federal de Ciências da Saúde de Porto Alegre/BR
/
Universidade Federal do Rio Grande do Sul/BR
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