Limited evidence of HCV transmission in stable heterosexual couples from Bahia, Brazil
Braz. j. infect. dis
;
13(4): 262-265, Aug. 2009. tab
Article
Dans Anglais
| LILACS
| ID: lil-539760
ABSTRACT
HCV infected patients frequently ask their physician about the risk of transmission to their partners. Although it is easy to answer that the risk does exist, it is difficult to quantify. We studied the transmission of HCV infection in stable heterosexual couples anti-HCV positive patients in hemodialytic therapy and their partners. Thirty-four couples were tested by third generation ELISA and RIBA. Blood samples of anti-HCV positive patients were evaluated by RT-PCR and detected sequences were genotyped by restriction fragment length polymorphism. Concordance of infection was observed in only one couple in which both subjects were in dialytic therapy. One other partner had two positive ELISA tests and an indeterminate RIBA, with negative RT-PCR, which may suggest a false positive or a previous resolved infection. Either sexual relations, sharing of personal items and history of parenteral exposure (hemodialysis, blood transfusion) could explain transmission in the only couple with concordant infection. We observed, in accordance with previous reports, that this risk is minimal or negligible in stable heterosexual couples.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Dialyse rénale
/
Hépatite C
/
Conjoints
/
Anticorps de l'hépatite C
/
Hétérosexualité
Type d'étude:
Etude diagnostique
/
Etude d'étiologie
/
Étude de prévalence
/
Facteurs de risque
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Braz. j. infect. dis
Thème du journal:
Maladies transmissibles
Année:
2009
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Ministry of Health/BR
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