Antifungal susceptibility profile of trichosporon isolates: correlation between CLSI and etest methodologies
Braz. j. microbiol
;
41(2): 310-315, Apr.-June 2010. tab
Article
Dans Anglais
| LILACS
| ID: lil-545335
ABSTRACT
The aim of the present study was to evaluate the antifungal susceptibility profile of Trichosporon species isolated from different sources employing the Clinical and Laboratory Standards Institute (CLSI) method and E-test method. Thirty-four isolates of Trichosporon spp. and six CBS reference samples were tested for their susceptibility to Amphotericin B, 5-flucytosine, Fluconazole, Itraconazole, Voriconazole and Terbinafine. All species showed high Minimun Inhibitory Concentrations (MIC) for Itraconazole and susceptibility to Fluconazole, The comparison among the results obtained by the CLSI method and E-test revealed larger discrepancies among 5-flucytosine and Itraconazole. The present work provides epidemiological data that could influence therapeutic choices. Furthermore, the comparison between different methodologies could help to analyze results obtained by different laboratories.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Trichosporon
/
Résistance des champignons aux médicaments
/
Deuteromycota
/
Prédisposition aux maladies
/
Mycoses
/
Antifongiques
Type d'étude:
Guide de pratique
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Braz. j. microbiol
Thème du journal:
Microbiologie
Année:
2010
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade Federal de Minas Gerais/BR
/
Universidade Federal de São João Del Rei/BR
/
Universidade do Vale do Paraíba/BR
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