Antiproliferative effect of indomethacin in Aedes albopictus (mosquito) cells
Rev. Ciênc. Méd. Biol. (Impr.)
; 8(1): 14-17, jan.-abr. 2009. graf
Article
de En
| LILACS, BBO
| ID: lil-545801
Bibliothèque responsable:
BR337.1
ABSTRACT
Non-steroidal and anti-inflammatory drugs (NSAIDs) are a class of pharmacological agents that are tradicionally used for their anti-cyclooxigenase properties in the treatment of inflammation and other associated diseases. Recently, however, it has been demonstrated that several NSAIDs exhibit antiproliferative effects in various animal models and in vitro experiments. In this paper we demonstrated that treatment of Aedes albopictus cells (mosquito) with indomethacin results in a reduction of normal growth rate. Cells treated with 100 mM indomethacin exhibited a profound time dependent reduction in their proliferation rate over the 96 h test period.
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Anti-inflammatoires non stéroïdiens
/
Indométacine
/
Aedes
langue:
En
Texte intégral:
Rev. Ciênc. Méd. Biol. (Impr.)
Thème du journal:
BIOLOGIA
/
MEDICINA
Année:
2009
Type:
Article