A description of genes of Corynebacterium pseudotuberculosis useful in diagnostics and vaccine applications
Genet. mol. res. (Online)
;
7(1): 252-260, Jan. 2008.
Article
Dans Anglais
| LILACS
| ID: lil-553792
ABSTRACT
Corynebacterium pseudotuberculosis, a Gram-positive intracellular pathogen, is the etiological agent of caseous lymphadenitis or CLA. This bacterium infects goats and sheep and causes great economic losses worldwide annually, mainly for goat producers. Despite its importance, CLA is still poorly characterized. However, with advances in the genomic field, many C. pseudotuberculosis genes have already been characterized, mainly those related to virulence such as phospholipase D. Here, we examined the use of the several available genes of C. pseudotuberculosis and reviewed their applications in vaccine construction, more efficient diagnostics for CLA, and control of this disease, among other applications.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Corynebacterium pseudotuberculosis
/
Infections à Corynebacterium
Type d'étude:
Etude diagnostique
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Genet. mol. res. (Online)
Thème du journal:
Biologie moléculaire
/
Génétique
Année:
2008
Type:
Article
/
descriptif de projet
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
UFBA/BR
/
UFMG/BR
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