Drug hypersensitivity in students from São Paulo, Brazil
Clinics
;
65(10): 1009-1011, 2010. tab
Article
Dans Anglais
| LILACS
| ID: lil-565985
ABSTRACT
BACKGROUND:
Drug hypersensitivity is responsible for substantial mortality and morbidity, and increased health costs. However, epidemiological data on drug hypersensitivity in general or specific populations are scarce.METHODS:
We performed a cross-sectional survey of 1015 university students, using a self-reported questionnaire.RESULTS:
The prevalence of self-reported drug hypersensitivity was 12,11 percent (123/1015). The most frequently implicated drugs were non-steroidal anti-inflammatory drugs (45,9 percent) and beta-lactam and sulfonamide antibiotics (25,40 percent). The majority of the patients reported dermatological manifestations (99), followed by respiratory (40), digestive (23) and other (19). Forty-five patients had an immediate type reaction, and 76,72 percent (89) had the drug by oral route.CONCLUSION:
The results showed that drug hypersensitivity is highly prevalent in university students, and that nonsteroidal anti-inflammatory drug and antibiotics (beta-lactams and sulfonamide) are the most frequently concerned drugs.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Étudiants
/
Hypersensibilité médicamenteuse
Type d'étude:
Étude observationnelle
/
Étude de prévalence
/
Facteurs de risque
Limites du sujet:
Adolescent
/
Adulte
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Clinics
Thème du journal:
Médicament
Année:
2010
Type:
Article
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