Elevada seroprevalencia de citomegalovirus, virus herpes simplex tipo 1 y virus Epstein Barr en adultos con virus de la inmunodeficiencia humana / High seroprevalence of cytomegalovirus, herpes simplex type 1 virus and Epstein Barr virus infection among human immunodefciency virus-infected adults
Rev. méd. Chile
;
138(7): 809-814, July 2010. tab
Article
Dans Espagnol
| LILACS
| ID: lil-567583
ABSTRACT
Background:
Cytomegalovirus (CMV), herpes simplex type 1 (HSV-1) and Epstein Barr virus (EBV) are latent persistent infections. Their reactivation may cause illnesses and death in human immunodefciency virus-infected (HIV) people. World wide seroprevalence of these viruses is over 50 percent. In Chile, information is not available.Aim:
To determine the seroprevalence of CMV, HSV-1 and EBV in Chilean HIV-infected adults. Patients andMethods:
A total of 400 HIV- infected adults aged 17 to 67 years (340 males) were studied during 2005 and 2006. CMV, HSV-1 and EBV serum antibodies were measured by enzyme-linked immunoabsorbent assay.Results:
The mean lapse from the diagnosis of HIV and serum testing was 67 months and 69.5 percent patients received antiretroviral therapy. Sixty seven percent of the sample were men who had sex with men (MSM). The seroprevalence for CMV, HSV-1 and EBV were 98.5, 92.2 and 99.7 percent, respectively. No patient had negative antibodies for all three viruses. Male patients that were negative for HSV-1 had a lower frequency of MSM than the rest of males (26 percent vs 62 percent, p < 0.01).Conclusions:
There is a high prevalence of positive antibodies against CMV, HSV-1 and EBV in Chilean adults infected with HIV. Specifc diagnostic tests and antiviral therapy should be available for these patients.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Infections à VIH
/
Infections à cytomégalovirus
/
Infections à virus Epstein-Barr
/
Herpès
Type d'étude:
Étude de prévalence
/
Facteurs de risque
Limites du sujet:
Adolescent
/
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Chili
langue:
Espagnol
Texte intégral:
Rev. méd. Chile
Thème du journal:
Médicament
Année:
2010
Type:
Article
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