Púrpura trombocitopénico inmune asociado a infección por virus hepatitis C en paciente hemofílico: Caso clínico / Immune thrombocytopenic purpura associated to hepatitis C virus infection: Report of one case
Rev. méd. Chile
;
138(9): 1140-1143, sept. 2010. ilus
Article
Dans Espagnol
| LILACS
| ID: lil-572021
ABSTRACT
Hepatitis C Virus (HCV) is a cause of secondary chronic immune thrombocytopenic purpura (ITP). We report a 43 year old man with mild Hemophilia A, who received blood transfusions during childhood, that consulted for epistaxis and ecchymoses. The laboratory showed a platelet count of 23.000/mm³, positive HCV serology and elevated transaminases. Steroids administered in pulses followed by oral doses resulted in a partial response requiring a second pulse and association of azathioprine. A steroidal diabetes appeared. Given his refractoriness, splenectomy and liver biopsy were performed. He continued on azathioprine maintaining a platelet count near 50.000/mm³ but continued with bleeding episodes. Liver biopsy showed a chronic active hepatitis.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Purpura thrombopénique idiopathique
/
Hépatite C chronique
/
Hémophilie A
Type d'étude:
Facteurs de risque
Limites du sujet:
Adulte
/
Humains
/
Mâle
langue:
Espagnol
Texte intégral:
Rev. méd. Chile
Thème du journal:
Médicament
Année:
2010
Type:
Article
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