Epidemiological and clinical characteristics of cutaneous leishmaniasis and their relationship with the laboratory data, south of Brazil
Braz. j. infect. dis
;
15(1): 12-16, Jan.-Feb. 2011. ilus, tab
Article
Dans Anglais
| LILACS
| ID: lil-576779
ABSTRACT
OBJECTIVE:
To evaluate clinical, epidemiological and laboratorial aspects for the understanding of the disease characteristics and its relationship with diagnostic tests.METHODS:
A retrospective, descriptive and analytical study involving 2,660 American cutaneous leishmaniasis (ACL) suspected patients from southern Brazil was undertaken between April 1986 and December 2005. Data on population characteristics and laboratory tests were obtained. Diagnostic laboratory tests used were direct search for Leishmania spp. (DS), Montenegro skin test (MST) and indirect immunofluorescent assay (IFA).RESULTS:
62.3 percent of patients were positive for at least one laboratory test. DS test was positive in 65.1 percent; MST in 92.3 percent and IFA in 70.0 percent. Although Cohen's Kappa test did not reveal any agreement with laboratory diagnosis for ACL, the association between MST and IFA tests increased positiveness to 98.9 percent; MST and DS to 97.2 percent; and IFA and DS to 85 percent. IFA and MST positiveness were higher among patients with < 2-month lesion-evolution time. Most ACL patients were male (72.6 percent) in the age range of 15-49 years, featuring lesions during two months or less (53.9 percent) and a cutaneous form of the disease (88.0 percent).CONCLUSION:
Findings suggest that for the adequate identification of ACL cases a combination of laboratory tests that involves the association of MST with at least another test should be used.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Leishmaniose cutanée
Type d'étude:
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adolescent
/
Adulte
/
Humains
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Braz. j. infect. dis
Thème du journal:
Maladies transmissibles
Année:
2011
Type:
Article
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