Acute effect of phosphodiesterase type 5 inhibitor on serum oxidative status and prolidase activities in men with erectile dysfunction
Clinics
;
65(12): 1311-1314, 2010. tab
Article
Dans Anglais
| LILACS
| ID: lil-578570
ABSTRACT
OBJECTIVES:
To investigate the acute effect of phosphodiesterase type 5 (PDE5) inhibitor on erectile dysfunction by evaluating serum oxidative status and prolidase activity.METHODS:
Serum samples of 36 patients with erectile dysfunction and 30 control cases were analyzed for total antioxidant status, total oxidant status, and prolidase activity, before and after the administration of tadalafil citrate.RESULTS:
Before and after tadalafil citrate administration, serum total antioxidant status, total oxidant status, and prolidase were 1.1+0.0 vs. 1.6 + 0.0 umol H2O2 Eq/L, 10.3+1.1 vs. 6.9 + 1.2 umol H2O2 Eq/L, and 236.4+19.5 vs. 228.2 + 19.2 U/L, respectively (p<0.0001 for all).CONCLUSIONS:
Evaluation of serum oxidative status and prolidase activity confirmed the beneficial acute effects of PDE5 inhibitor in patients with erectile dysfunction.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Carbolines
/
Stress oxydatif
/
Dipeptidases
/
Dysfonctionnement érectile
Type d'étude:
Étude observationnelle
Limites du sujet:
Adulte
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Clinics
Thème du journal:
Médicament
Année:
2010
Type:
Article
Pays d'affiliation:
Turquie
Institution/Pays d'affiliation:
Harran University/TR
/
Sanliurfa Research Hospital/TR
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS