Cognitive awareness of carbohydrate intake does not alter exercise-induced lymphocyte apoptosis
Clinics
;
66(2): 197-202, 2011. graf, tab
Article
Dans Anglais
| LILACS
| ID: lil-581501
ABSTRACT
OBJECTIVE:
The purpose of this investigation was to determine whether cognitive awareness of carbohydrate beverage consumption affects exercise-induced lymphocyte apoptosis, independent of actual carbohydrate intake.INTRODUCTION:
Carbohydrate supplementation during aerobic exercise generally protects against the immunosuppressive effects of exercise. It is not currently known whether carbohydrate consumption or simply the knowledge of carbohydrate consumption also has that effect.METHODS:
Endurance trained male and female (N = 10) athletes were randomly assigned to one of two groups based on either a correct or incorrect cognitive awareness of carbohydrate intake. In the incorrect group, the subjects were informed that they were receiving the carbohydrate beverage but actually received the placebo beverage. Participants completed a 60-min ride on a cycle ergometer at 80 percent VO2peak under carbohydrate and placebo supplemented conditions. Venous blood samples were collected at rest and immediately after exercise and were used to determine the plasma glucose concentration, lymphocyte count, and extent of lymphocyte apoptosis. Cognitive awareness, either correct or incorrect, did not have an effect on any of the measured variables.RESULTS:
Carbohydrate supplementation during exercise did not have an effect on lymphocyte count or apoptotic index. Independent of drink type, exercise resulted in significant lymphocytosis and lymphocyte apoptosis (apoptotic index at rest = 6.3 ± 3 percent and apoptotic index following exercise = 11.6 ± 3 percent, P<0.01).CONCLUSION:
Neither carbohydrate nor placebo supplementation altered the typical lymphocyte apoptotic response following exercise. While carbohydrate supplementation generally has an immune-boosting effect during exercise, it appears that this influence does not extend to the mechanisms that govern exercise-induced lymphocyte cell death.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Endurance physique
/
Conscience immédiate
/
Hydrates de carbone alimentaires
/
Lymphocytes
/
Apoptose
Type d'étude:
Essai clinique contrôlé
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Clinics
Thème du journal:
Médicament
Année:
2011
Type:
Article
Pays d'affiliation:
États-Unis d'Amérique
Institution/Pays d'affiliation:
University of Houston/US
/
Western Kentucky University/US
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