Risk factors for oral candidiasis in Brazilian HIV-infected adult patients
Braz. j. oral sci
;
9(4): 470-474, Oct.-Dec. 2010. tab
Article
Dans Anglais
| LILACS, BBO
| ID: lil-582280
ABSTRACT
Aim:
The goals of this study were 1) to estimate the prevalence of oral candidiasis (OC) in a sample of Brazilian HIV-infected adult patients, and 2) to investigate the risk factors for HIVassociated OC in this sample.Methods:
This case-control study included 112 HIV-infected patients treated between 2002 and 2004 at a clinic for sexually transmitted diseases. Data were collected from medical records and clinical examinations. Diagnosis of OC was performed in accordance with the International Classification System and cytological features. Seventeen clinical and laboratorial variables were registered. Univariate analyses were performed on all variables. Multiple logistic regression techniques were used to develop a model and identify the set of variables that may predict risk factors in HIV-infected adult patients with OC.Results:
Prevalence of OC was 31.3%. OC was associated with oral hairy leukoplakia (OHL) [p<0.001; odds ratio (OR) = 10.2 (95%CI 4.0-26.0)], previous use of fluconazole [p<0.001; OR=27.4 (95%CI 8.1-92.0)] and viral load [p=0.042; OR=2.3 (95%CI 1.0-5.3)].Conclusions:
These results are important for the development of strategies to eliminate these risk factors and significantly reduce OC in HIV-infected patients.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Candidose buccale
/
Infections à VIH
/
Thérapie antirétrovirale hautement active
/
Antifongiques
Type d'étude:
Essai clinique contrôlé
/
Etude d'étiologie
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Humains
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Braz. j. oral sci
Thème du journal:
Dentisterie
Année:
2010
Type:
Article
/
descriptif de projet
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Faculdades Pitágoras/BR
/
Federal University of Minas Gerais/BR
/
Federal University of Vales Jequitinhonha and Mucuri/BR
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