Leishmania infection in humans, dogs and sandflies in a visceral leishmaniasis endemic area in Maranhão, Brazil
Mem. Inst. Oswaldo Cruz
;
106(2): 207-211, Mar. 2011. mapas, tab
Article
Dans Anglais
| LILACS
| ID: lil-583947
ABSTRACT
Leishmania infection in humans, dogs and sandflies was examined in the endemic visceral leishmaniasis (VL) municipality of Raposa, state of Maranhão, Brazil. In this study, we examined Leishmania chagasi infection in the blood serum of both humans and Canis familiaris and the natural Leishmania sp. infection rate in the sandfly vector, Lutzomyia longipalpis. Enzyme-linked immunosorbent assay, indirect immunofluorescence reaction and polymerase chain reaction were performed to detect Leishmania infections in humans, dogs and sandflies, respectively. Overall, 186 out of 986 studied human beings were infected with L. chagasi parasites, representing an infection prevalence of 18.9 percent. An even higher infection rate was detected in dogs, where 66 (47.8 percent) out of 138 were infected. Among all Lu. longipalpis captured (n = 1,881), only 26.7 percent were females. The Leishmania infection frequency for the vector Lu. longipalpis was 1.56 percent. Remarkably, all infected sandflies were found in the peridomiciliary area. Furthermore, a high incidence of asymptomatic forms of VL in the human and canine populations was observed. The results of this study suggest autochthonous transmission of L. chagasi in this endemic area for visceral leishmaniasis because infection by Leishmania sp. was identified in all important elements of the transmission chain.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Psychodidae
/
Maladies endémiques
/
Maladies des chiens
/
Vecteurs insectes
/
Leishmaniose viscérale
Type d'étude:
Facteurs de risque
Limites du sujet:
Animaux
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
Médecine tropicale
/
Parasitologie
Année:
2011
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Fiocruz/BR
/
Universidade Federal do Maranhão/BR
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