Induction of Zenk protein expression within the nucleus taeniae of the amygdala of pigeons following tone and shock stimulation
Braz. j. med. biol. res
;
44(8): 762-766, Aug. 2011. ilus
Article
Dans Anglais
| LILACS
| ID: lil-595720
ABSTRACT
In this study, we evaluated the expression of the Zenk protein within the nucleus taeniae of the pigeon’s amygdala (TnA) after training in a classical aversive conditioning, in order to improve our understanding of its functional role in birds. Thirty-two 18-month-old adult male pigeons (Columba livia), weighing on average 350 g, were trained under different conditions with tone-shock associations (experimental group; EG); with shock-alone presentations (shock group; SG); with tone-alone presentations (tone group; TG); with exposure to the training chamber without stimulation (context group; CG), and with daily handling (naive group; NG). The number of immunoreactive nuclei was counted in the whole TnA region and is reported as density of Zenk-positive nuclei. This density of Zenk-positive cells in the TnA was significantly greater for the EG, SG and TG than for the CG and NG (P < 0.05). The data indicate an expression of Zenk in the TnA that was driven by experience, supporting the role of this brain area as a critical element for neural processing of aversive stimuli as well as meaningful novel stimuli.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Gènes précoces
/
Facteur de transcription EGR-1
/
Peur
/
Amygdale (système limbique)
Type d'étude:
Études d'évaluation
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Braz. j. med. biol. res
Thème du journal:
Biologie
/
Médicament
Année:
2011
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade Metropolitana de Santos/BR
/
Universidade de Campinas/BR
/
Universidade de São Paulo/BR
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