Research of the origin of a particular Tunisian group using a physical marker and Alu insertion polymorphisms
Genet. mol. biol
;
34(3): 371-376, 2011. ilus, tab
Article
Dans Anglais
| LILACS
| ID: lil-595985
ABSTRACT
The aim of this study was to show how, in some particular circumstances, a physical marker can be used along with molecular markers in the research of an ancient people movement. A set of five Alu insertions was analysed in 42 subjects from a particular Tunisian group (El Hamma) that has, unlike most of the Tunisian population, a very dark skin, similar to that of sub-Saharans, and in 114 Tunisian subjects (Gabes sample) from the same governorate, but outside the group. Our results showed that the El Hamma group is genetically midway between sub-Saharan populations and North Africans, whereas the Gabes sample is clustered among North Africans. In addition, The A25 Alu insertion, considered characteristic to sub-Saharan Africans, was present in the El Hamma group at a relatively high frequency. This frequency was similar to that found in sub-Saharans from Nigeria, but significantly different from those found in the Gabes sample and in other North African populations. Our molecular results, consistent with the skin color status, suggest a sub-Saharan origin of this particular Tunisian group.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Polymorphisme génétique
/
Population
/
Tunisie
/
Pigmentation de la peau
/
Séquences Alu
Limites du sujet:
Humains
Pays comme sujet:
Afrique
langue:
Anglais
Texte intégral:
Genet. mol. biol
Thème du journal:
Génétique
Année:
2011
Type:
Article
Pays d'affiliation:
Espagne
/
Tunisie
Institution/Pays d'affiliation:
Centre Régional de Transfusion Sanguine de Gabès/TN
/
Universitat de Barcelona/ES
/
University of Monastir/TN
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