Chemical composition and biological screening of Capsella bursa-pastoris
Rev. bras. farmacogn
;
21(4): 635-643, jul.-ago. 2011. graf, tab
Article
Dans Anglais
| LILACS
| ID: lil-596230
ABSTRACT
Capsella bursa-pastoris (L.) Medik. (Brassicaceae) is a wild herb with high nutritional value that can be eaten raw or cooked. A metabolomic study was performed with different extracts of its aerial parts that were tested concerning their antiradical, acetylcholinesterase inhibitory and antibacterial activities. Phenolic compounds were identified and quantified by HPLC-DAD, organic acids and amino acids were determined by HPLC-UV, while free fatty acids and sterols were analysed by GC-ITMS. The vegetal material was rich in kaempferol-3-O-rutinoside (mean value 2247.09 mg/kg of dry plant), quinic acid (95628.00 mg/kg of dry plant), arginine (mean value of 1.18 mg/kg of dry plant), palmitic acid (284.48 mg/kg) and β-sitosterol (28 percent). The extracts presented a concentration-dependent antiradical activity (against DPPH, O2- and LOO), being most effective against NO (EC25 0.20 µg/mL). In addition, the extracts were also acetylcholinesterase inhibitors and antibacterial active, revealing that, besides the plant's good nutritional value, it presents important biological properties as well.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Type d'étude:
Etude diagnostique
/
Étude de dépistage
langue:
Anglais
Texte intégral:
Rev. bras. farmacogn
Thème du journal:
Pharmacie
Année:
2011
Type:
Article
/
descriptif de projet
Pays d'affiliation:
Danemark
/
Portugal
Institution/Pays d'affiliation:
Universidade do Porto/PT
/
University of Copenhagen/DK
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS