UV-induced growth inhibition in the trypanosomatid Crithidia fasciculata
Braz. j. med. biol. res
;
21(3): 493-7, Mar. 1988. ilus
Article
Dans Anglais
| LILACS
| ID: lil-60238
ABSTRACT
The effects of short ultraviolet (253 mm) radiation on the growth of the trypanosomatid flagellate Crithidia fasciculada were studied in liquid medium and nutrient agar plates. Cell duplication was completely inhibited after exposure of the flagellates to doses equal to or higher than 50 J/m2. The UV-induced lag period was dose-dependent. Survival was reduced to 1% after exposure of the parasites to 200 J/m2. Ultrastructural changes after the lag period were studied by transmission electron microscopy. Changes of the kinetoplast network structure and sometimes of the mitochondrial matrix were observed. The existence of DNA repair mechanisms in this protozoan is discussed
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Indice:
LILAS (Amériques)
Sujet Principal:
Dose de rayonnement
/
Rayons ultraviolets
/
Division cellulaire
/
Crithidia
/
Réparation de l'ADN
Type d'étude:
Etude diagnostique
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Braz. j. med. biol. res
Thème du journal:
Biologie
/
Médicament
Année:
1988
Type:
Article
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