A novel property of an aqueous guaraná extract (Paullinia cupana): inhibition of platelet aggregation in vitro and in vivo
Braz. j. med. biol. res
;
21(3): 535-8, Mar. 1988. tab
Article
Dans Anglais
| LILACS
| ID: lil-60247
ABSTRACT
Aqueous extracts of guaraná were studied in terms of effects on the aggregation of human and rabbit platelets. Guaraná extracts have anti-aggregatory and de-aggregatory actions on platelet aggragation induced by ADP or arachidonate but not by collagen. The active material was shown to be water soluble and heat resistant and appeared to be different from salicylates, nicotinic acid or known xanthines. Guaraná extracts inhibited platelet aggregation in rabbits following either intravenous or oral administration
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Indice:
LILAS (Amériques)
Sujet Principal:
Plantes médicinales
/
Extraits de plantes
/
Agrégation plaquettaire
Limites du sujet:
Animaux
/
Humains
langue:
Anglais
Texte intégral:
Braz. j. med. biol. res
Thème du journal:
Biologie
/
Médicament
Année:
1988
Type:
Article
/
Congrès et conférence
/
descriptif de projet
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