Mielograma de ratas com disfunção tireoidiana / Bone marrow examination in rats with thyroid dysfunction
Arq. bras. med. vet. zootec
;
63(5): 1246-1250, out. 2011. ilus, tab
Article
Dans Portugais
| LILACS
| ID: lil-605855
ABSTRACT
The cells of the myelo id, lymphoid , and erythroid lineage s of the bone marrow were quantified in rats with hypo and hyperthyroidism. Fifteen Wistar rats were divided into three groups hypothyroid (n=5), hyperthyroid (n=5) , and control (n=5). Three months after the onset of the treatment s, euthanasia was performed . Bone marrow was aspirated from femurs of each animal to perform smear s that were stained with Quick Panoptic. T he percentage s of rubroblast, prorubrocyte, metarubrocyte, myeloblast, promyelocytes, metamyelocytes, myel ocytes, segmented, eosinophils, basophils, lymphocytes, plasma cells and monocytes in were determined a total of 500 cells. The bone marrow of animals with hypothyroidism had hypoplasia. The myeloiderythroid ratio was higher in animals with thyroid dysfun ction. In hypo and hyperthyroidism, there was a significant reduction of the percentage of rubrocyte, metarubrocyte , and lymphocytes and increase of myelocytes and segmented cells. In hypothyroidism, there was a significant increase in the percentage of me tamyelocytes. It is c oncluded that both hypo and hyperfunction of thyroid increase the myeloiderythroid ratio by increasing the number of cells of the myeloid lineage and reducing the cells of the erythroid lineage.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Rats
/
Hormones thyroïdiennes
/
Hyperthyroïdie
/
Hypothyroïdie
Limites du sujet:
Animaux
langue:
Portugais
Texte intégral:
Arq. bras. med. vet. zootec
Thème du journal:
Médecine vétérinaire
Année:
2011
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
UFMG/BR
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