Nuevos anticoagulantes orales / New oral anticoagulant drugs
Rev. méd. Chile
; 139(10): 1347-1355, oct. 2011. ilus, tab
Article
de Es
| LILACS
| ID: lil-612205
Bibliothèque responsable:
BR1.1
ABSTRACT
Thromboembolic disease (TED) is the leading cause of morbidity and mortality worldwide. The hallmark of oral long-term anticoagulant therapy has been the use of vitamin K antagonists, whose anticoagulant effect is exerted inhibiting vitamin K epoxide reductase. Warfarin and acenocoumarol are the most commonly used. In the last five years several new drugs for long term anticoagulation have been developed, which can inhibit single clotting factors with the purpose of improving drug therapeutic range and, ideally, minimizing bleeding risks. This review addresses the state of the art on the clinical use of inhibitors of activated factor X and thrombin.
Mots clés
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Vitamine K
/
Thrombine
/
Facteur Xa
/
Anticoagulants
Limites du sujet:
Humans
langue:
Es
Texte intégral:
Rev. méd. Chile
Thème du journal:
MEDICINA
Année:
2011
Type:
Article