Phasic or terminal detrusor overactivity in women: age, urodynamic findings and sphincter behavior relationships
Int. braz. j. urol
;
37(6): 773-780, Nov.-Dec. 2011. tab
Article
Dans Anglais
| LILACS
| ID: lil-612762
ABSTRACT
OBJECTIVES:
To search for relationships between phasic (P) and terminal (T) DO with age, urodynamic findings and sphincter behavior during involuntary detrusor contraction in woman. MATERIALS ANDMETHODS:
Urodynamic studies (triple lumen catheter 7F, seated position) of 164 successive women referred for LUTS with diagnosis of DO were reviewed. Patients were stratified in 4 sub-groups pre- (18-44y), peri- (45-54 y), post-menopause (55-74 y) and oldest old (≥ 75 y). The urethral sensor was positioned at the level of the maximum urethral closure pressure for sphincter behavior analysis. A variation of at least 5 cmH2O in pressure (detrusor or urethra) was chosen to assert DO or sphincter response. Sphincter response was classified as relaxation (re) before or during DO, or steady (st).RESULTS:
Occurrence of P and TDO was similar 77 P and 87 T. The PDO group was significantly younger (p = 0.0003). TDO was more frequent in patients with a history of neurological disease. The percentage of PDO remained almost constant in age groups, while that of TDO increased with age from 6.7 percent to 23.2 percent (p = 0.0013). Uninhibited contraction occurred at a smaller bladder volume in the P group 149 ± 95 vs. 221 ± 113 mL (p < 0.0001). Steady sphincter predominated in the TDO subgroup 45.9 percent vs. 32.1 percent and increased significantly in each DO sub-group of ³ 75y.CONCLUSION:
Steady sphincter during both P and TDO, and occurrence of TDO appear as specific of aging. The last result could be related to structural changes in the detrusor muscle with aging.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Urètre
/
Incontinence urinaire d'effort
/
Urodynamique
/
Vessie hyperactive
Type d'étude:
Etude diagnostique
Limites du sujet:
Adolescent
/
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
langue:
Anglais
Texte intégral:
Int. braz. j. urol
Thème du journal:
Urologie
Année:
2011
Type:
Article
Pays d'affiliation:
France
Institution/Pays d'affiliation:
Université Pierre et Marie Curie/FR
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